Dr Douglas Macdonald


Dr Douglas Macdonald


Gastroenterologist & Hepatologist

Dr Doug Macdonald graduated in 2001 with Honours and Distinctions in Medical sciences and Clinical Medicine.  He trained as a junior doctor on the Hammersmith SHO rotation (now Imperial College Hospital) and King’s College Hospital Liver Transplant Unit before working as a research fellow in infectious diseases in Lima, Peru in 2005. He returned to London for specialist registrar training in Gastroenterology and Hepatology based in the Imperial College Hospital Trust. He completed a PhD in Virology and Immunology at University College London between  2008-2012 and was awarded a fellowship at Yale University in 2012. He has been a Consultant Hepatologist at the Royal Free Hospital since 2013, leading the introduction of new oral antiviral agents for hepatitis C.

Dr Macdonald’s main research interest is the interaction between viruses and the liver and digestive system. His publications and ongoing work focus on means of harnessing viruses as vaccines to treat infections and cancers. He is a faculty member of a number of courses teaching communication skills and medical ethics and has published two textbooks guiding trainee doctors through their membership of the Royal College of Physician exams. He is currently developing applications with computer science students at UCL which aim to enhance rather than distract from a human and empathic interaction between doctor and patient.

Year qualified


Country of qualification


Languages spoken

English, Spanish, French


  • Gastroenterology
  • Hepatology


  • RCP
  • MDU
  • BMA

Procedures offered

  • Upper GI Endoscopy
  • Colonoscopy
  • Fibroscan

Clinical interests

  • Viral hepatitis treatment in complex patients
  • Drug-induced liver injury
  • Liver cancer and surveillance
  • Mixed cryoglobulinaemia syndrome
  • Clinical capacity-building in resource-limited countries


Research interests

  • Viral vector vaccines for treatment or prevention of influenza
  • Viral hepatitis and liver cancer
  • Surveillance strategies for liver cancer
  • Gene therapy with lentiviral vectors

Dr Douglas Macdonald, Gastroenterologist & Hepatologist is available to be seen for consultations at Royal Free London

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