Mr Leye Ajayi

MBBS(Lon) FRCS(Eng), MD (Lon), FRCS(Urol)

Consultant Urological Surgeon

Mr Leye Ajayi is a Consultant Urological Surgeon and Clinical Lead for Endourology at the Royal Free Hospital. He specialises in minimally invasive surgery for urinary tract stone disease and Benign Prostate Hyperplasia (BPH). His general urology practice includes andrology, rapid access prostate clinics, and haematuria (blood in urine) assessments.

Mr Ajayi established the Aquablation therapy programme at the Royal Free Hospital and has extensive experience performing this advanced procedure. Surgeons from across the UK and Europe attend his theatre sessions to gain insight into the technology and surgical technique.

He was awarded an MD for his research into the molecular biology of prostate cancer and has published widely in this field as well as in urinary tract stone disease. He is Course Director of an international masterclass in complex stone disease and is one of a small number of surgeons in the UK performing percutaneous nephrolithotomy (PCNL) in the supine position, with significant expertise in this complex procedure.

Mr Ajayi is an Associate Member of the Endourology Section of the European Association of Urology. He has performed live surgery at the Association’s Annual Congress in London (2017), Copenhagen (2018), Barcelona (2019), Virtual Congress (2021), Paris (2024) and London (2026).

He has been invited to faculty roles at numerous European meetings and represented the European School of Urology(ESU) during masterclasses in Barcelona (2021–2024). Additional invited faculty and live surgery roles include:

Balkan Urology Society Meeting – Belgrade (2022)
Uro-Tech 22 – Istanbul (2022)
Faculty and cadaveric endourology course – Cape Town
International Meeting on Technology and Training in Endourology – Turin (Faculty 2022; Live Surgery 2023 & 2025)
Belgian Endourological Association Meeting (2023 & 2025)

Mr Ajayi served as moderator for the Journal of Endourology Podcast on stone disease (2020–2021) and is faculty for the Société Internationale d'Urologie (SIU) Grand Round on controversies in urinary stone management.

Hospital Locations

Royal Free Hospital

Year qualified

1993

Specialities

Urology

Memberships

Royal College of Surgeons of England
British Association of Urological Surgeons
European Association of Urology
European Association of Urology Section of Uro-Technology (ESUT)
European School of Urology
Royal Society of Medicine
Endourological Society
Société Internationale d’Urologie

Procedures offered

Aquablation therapy
Supine PCNL, mini-PCNL and endoscopic combined intrarenal surgery (ECIRS)
Ureteroscopy (flexible and semirigid) - for stones or upper tract urothelial cancer (UTUC)
Transurethral resection of prostate (TURP)
Transurethral resection of bladder tumour (TURBT)
Lithotripsy
Peno-scrotal procedures- hydrocele repair, epididymal cyst excision, varicocele treatment, vasectomy and circumcision
Holmium and thulium fibre laser (TFL) technology for stone disease

Special interests

Mr Ajayi offers rapid access one stop urinary stones, haematuria and prostate assessment. His main specialist interests are in minimally invasive laser surgery for complex kidney and ureteric stone disease including lithotripsy. He also has an interest in andrology.

Published papers

Bibliography Peer Review Publications

Factors Predicting Outcomes of Supine Percutaneous Nephrolithotomy: Large Single-Centre Experience Yasmin Abu-Ghanem, Luke Forster, Pramit Khetrapal, Gidon Ellis, Paras Singh, Rohit Srinivasan, Rajesh Kucheria, Anuj Goyal, Darrell Allen, Antony Goode, Dominic Yu and Leye Ajayi. J. Pers. Med. 2022, 12, 1956
Emergency Primary Ureteroscopy for Acute Ureteric Colic—From Guidelines to Practice Yasmin Abu-Ghanem, Christina Fontaine, Radha Sehgal, Luke Forster, Neeta Verma, Gidon Ellis, Rajesh Kucheria, Darrell Allen, Paras Singh, Anuj Goyal and Leye Ajayi J. Pers. Med. 2022, 12, 1866
Primary Definitive Treatment versus Ureteric Stenting in the Management of Acute Ureteric Colic: A Cost-Effectiveness Analysis Radha Sehgal, Yasmin Abu-Ghanem, Christina Fontaine, Luke Forster, Anuj Goyal, Darrell Allen, Rajesh Kucheria, Paras Singh, Gidon Ellis and Leye Ajayi J. Pers. Med. 2022, 12, 1773.
Supine Percutaneous Nephrolithotomy in the Galdako-Modified Valdivia Position: A High-Volume Single Center Experience. Curry D, Srinivasan R, Kucheria R, Goyal A, Allen D, Goode A, Yu D, Ajayi L. Journal of Endourology. 2017 Aug 23.
Supine Percutaneous nephrolithtomy for Staghorn calculi prospectively recorded experience in a single tertiary referral endourology unit. John Withington*, David Curry, Sarah Tang, Asheesh Kaul, Helena Gresty, Anthony Goode, Nick Woodward, Dominic Yu, Anuj Goyal, Rajesh Kucheria, Darrell Allen, Leye Ajayi, The Journal of Urology. Vol. 197, No. 4S, Supplement, Monday, May 15, 2017
An Insight into supine PCNL. Sarah Tang, Leye Ajayi. Urology News, December 2016, Vol 21, No 1, page 21-23
Renal stone disease, Leye Ajayi, Philippe Jaeger, William Robertson and Robert Unwin. Medicine, Volume 35, Issue 8, August 2007, Pages 415-419
MD Thesis. Investigation of a tumour suppressor gene at Chromosome 10q23.3 in prostate cancer. Adeleye Ajayi. University of London 2006.
Adult nocturnal enuresis: guide to causes and treatment. Amanda Williams, Leye Ajayi, Harry Naerger.Prescriber. Vol: 16 Issue: 24, 19^th December 2005
Adult Nocturnal enuresis. Ajayi LA, Naerger HGA. Prescriber.Vol 12, 19^th June 2001.
The Expression profile and genomic organisation of the tumour Suppressor Gene PTEN. Hamilton JA, Ajayi LA, Stewart LMD, Roberts KG, Kaisary AV, Snary D. Br J Cancer. May 2000.82(10) 1671-6

Abstracts published

Upper pole renal puncture in supine percutaneous nephrolithotomy – 9 year experience from a single tertiary stone unit. Moghul M. , Withington J. , Goyal A. , Kucheria R. , Allen D. , Ajayi L. European Urology Supplement 18(1):e2033-e2034 · March 2019
Supine percutaneous nephrolithotomy in the obese patient. J Withington, Moghul M, Goyal A. , Kucheria R. , Allen D. , Ajayi L. European Urology Supplement – 18(1):e2036 · March 2019
PD17-08 The effects of medically expulsive therapy METon Spontaneous stone passage (SSP) in patients presenting with acute ureteric colic. Taimur Shah, Leye Ajayi et al Journal of Urology 199(4):e387-e388 · April 2018
Medically expulsive therapy MET has no benefit in improving_ pontaneous stone passage SSP in patients presenting with acute ureteric colic Results from the MIMIC study. Taimur Shah, Leye Ajayi et al European Urology Supplement – 18(1):e2036 · March 2018
Supine Percutaneous nephrolithtomy for Staghorn calculi prospectively recorded experience in a single tertiary referral endourology unit. John Withington*, David Curry, Sarah Tang, Asheesh Kaul, Helena Gresty, Anthony Goode, Nick Woodward, Dominic Yu, Anuj Goyal, Rajesh Kucheria, Darrell Allen, Leye Ajayi, London, UK. The Journal of urology. Vol. 197, No. 4S, Supplement, Monday, May 15, 2017
Percutaneous Nephrolithotomy in the Extended Lithotomy Position – A New Approach to an Old Problem? J Bycroft, S Pridgeon, D Yu, N Woodward, A Goode and L Ajayi BJUi June 2010- Volume 106, Issue Supplement s1. Pages v–vi, 1–66 Abstract 167
“Pass the ball”-simultaneous antegrade and retrograde endoscopic fragmentation of stones in the extended lithotomy position for percutaneous nephrolithotomy. Leye Ajayi, M. Hussain, Dominic Yu, Nick Woodward, Neil Davis, Antony Goode. European Urology Association. Stockholm 17^th -21 March 2009
Our initial experience with extended lithotomy position for percutaneous nephrolithotomy. Leye Ajayi, M. Hussain, Dominic Yu, Nick Woodward, Neil Davis, Anthony Goode. Urolithiasis Research, 2008
The true value of Hexvix® photodynamic diagnosis following intravesical Bacilli Calmette Guerin treatment for superficial bladder cancer. Eleanor Ray, Kay Thomas, Leye Ajayi, Kathryn Chatterton, M S Khan, Tim O’Brien. American Urologic Association Annual Meeting. California May 19-24, 2007.
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. Journal of Endourology. August 15, 2006, 20(supplement 1): A97-A298.
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. BJUi 2006 vol 97 suppl 5 ; page 8 abstract 04.
A prospective audit of flexible ureterenoscopy and holmium laser lithotripsy for treatment of Intrarenal Calculi. J Henderson, L Ajayi, K Thomas, P Dasgupta , R. Tiptaft, J Glass. European Urology Supplements Volume 5, Issue 2, April 2006, Page 108
A prospective comparison of flexible ureterenoscopy and holmium laser versus electrohydrolic lithotripsy for ESWL resistant upper tract calculi. Ajayi LA, Henderson JR, Thomas K, Dasgupta P, Glass JMG, Tiptaft RC. BJUi 2005 vol 95 suppl 5 ; page 35 abstract P14
The use of Ureteral access sheaths and flexible ureteroscopy; A marriage made in Heaven? L.Ajayi, J.Allan, B.Montgomery, H.Naerger, E.Palfrey. BAUS Glasgow 2002. BJUi 2002 vol 90 suppl 1; page 52 abstract P098.
Use of Microsatellite markers as Genetic markers to identify risks of tumour progression. Ajayi LA, Stewart LMD, Roberts KG, Snary D, Kaisary AV. BJU 2000 vol 86; 3: Page 392

Podium presentations

MP02-12 – The utility and safety of diagnostic ureteroscopy in the diagnosis of upper tract urothelial carcinoma (UTUC): the experience of a high volume centre. T Birks, N. Pindoria, C. Cumby, R Kucheria, A. D Allen, Goyal, L Ajayi, G Ellis. World Congress of Endourology- Abu Dhabi 30^th October 2019
MP23-12 – Outcomes of non-lower pole puncture for supine PCNL: a multi-centre study. Carlos Mejia Arbalaez, Mehmet Gokce , Braulio Manzo, Mariano Gonzalez, Silvia Proietti , Leye Ajayi, Jose Ernesto Torres Garcia; Alan Yaghoubian, Guido Giusti, Pedro Daels; Christian Cristallo; Giuseppe Saitta, Theodore Birks; Brian Eisner. World Congress of Endourology- Abu Dhabi 1^st November 2019
MP23-16 – Percutaneous nephrolithotomy in the transplant kidney – a prospective 20 year multicentre experience Theodore Birks, Cristina Ferreiro; John Withington, Masood Moghul, Carlos Torrecilla, Francesc Vigués, Oriol Angerri Feu, Alberto Breda, Esteban Emiliani, Leye Ajayi. World Congress of Endourology- Abu Dhabi 1^st November 2019
Supine percutaneous nephrolithotomy in the obese patient. J Withington, Moghul M, Goyal A. , Kucheria R. , Allen D. , Ajayi L. European Association of Urology conference- Barcelona March 2019
Upper pole renal puncture in supine percutaneous nephrolithotomy – 9 year experience from a single tertiary stone unit. Moghul M. , Withington J. , Goyal A. , Kucheria R. , Allen D. , Ajayi L. European Association of Urology conference- Barcelona March 2019
Supine percutaneous nephrolithotomy in the obese patient. J Withington, M Moghul, D Allen, L Ajayi. World Congress of Endourology – Paris September 2018
Supine Percutaneous Nephrolithotomy for Staghorn Calculi. J Withington, M Moghul, D Allen, L Ajayi.World Congress of Endourology – Paris September 2018
Delays in Emergency Urological Stent Insertions – Case for an Emergency Pathway for Obstructing Stones. M Moghul, J Withington, A Goyal, R Kucheria, D Allen, L Ajayi. World Congress of Endourology – Paris September 2018
Supine Percutanours nephrolithotomy in horseshoe shaped kidneys- a case series. Goonewardene SS, Goyal A, Kucheria R, Allen D, Goode A, Yu, D, Ajayi L. Société Internationale d’Urologie- Libson 2017
Supine Percutaneous nephrolithtomy for Staghorn calculi prospectively recorded experience in a single tertiary referral endourology unit. John Withington, David Curry, Sarah Tang, Asheesh Kaul, Helena Gresty, Anthony Goode, Nick Woodward, Dominic Yu, Anuj Goyal, Rajesh Kucheria, Darrell Allen, Leye Ajayi, American Urology Association (AUA) May, 2017.
An Insight into supine PCNL. Sarah Tang, Leye Ajayi. Urology News, December 2016, Vol 21, No 1, page 21-23
Management of prostate cancer in Africans in the Diaspora- L. Ajayi, London (GB). Joint Session of the European Association of Urology (EAU) and the Pan- African Urological Surgeons’ Association (PAUSA- EAU- March 2016- Munich
Simultaneous flexible ureterenoscopy and supine percutaneous nephrolithotomy (sPCNL David Curry, Anuj Goyal, Anthony Goode2, Nick Woodward2, Dominic Yu2, Darrell Allen1, Leye Ajayi World Congress of Endourology – October 2015
Does body mass index (BMI) predict outcome in supine percutaneous nephrolithotomy (sPCNL)? Paras B Singh1, Ramin Mandegaran1 , Anthie Papadopoulous2 , Neil Davies2, Anthony Goode2, Nick Woodward2, Dominic Yu2, Darrell Allen1, Leye Ajayi SIU UK Section Meeting “Stones, Shocks & Scopes” 22^nd November 2013
Supine percutaneous nephrolithotomy (s-PCNL): upper pole access is possible without increased risk of complications. Paras B Singh¹, Ramin Mandegaran¹ , Anthie Papadopoulous² , Neil Davies², Anthony Goode², Nick Woodward², Dominic Yu², Darrell Allen¹, Leye Ajayi¹ SIU UK Section Meeting “Stones, Shocks & Scopes”- 22^nd November 2013
Does body mass index (BMI) predict outcome in supine percutaneous nephrolithotomy (sPCNL)? Paras B Singh1, Ramin Mandegaran1 , Anthie Papadopoulous2 , Neil Davies2, Anthony Goode2, Nick Woodward2, Dominic Yu2, Darrell Allen1, Leye Ajayi1 1^st ESD “Experts in Stone Disease” Conference -Dubai, December 13-15 2012
Supine percutaneous nephrolithotomy (s-PCNL): upper pole access is possible without increased risk of complications. Paras B Singh¹, Ramin Mandegaran¹ , Anthie Papadopoulous² , Neil Davies², Anthony Goode², Nick Woodward², Dominic Yu², Darrell Allen¹, Leye Ajayi 1^st ESD “Experts in Stone Disease” Conference -Dubai, December 13-15 2012
Supine percutaneous nephrolithotomy (s-PCNL): our experience with 103 consecutive cases. Paras B Singh1, Vimoshan Arumuham1, Neil Davies2, Anthony Goode2, Nick Woodward2, Anthie Papadopoulous2, Dominic Yu2, Darrell Allen1, Leye Ajayi1 BAUS section of Endourology- Birmingham, April 2012
Percutaneous Nephrolithotomy in the Extended Lithotomy Position – A New Approach to an Old Problem? J Bycroft, S Pridgeon, D Yu, N Woodward, A Goode and L Ajayi. British association of Urological Surgeons-Manchester 2010
“Pass the ball”- simultaneous antegrade and retrograde endoscopic fragmentation of stones in the extended lithotomy position for percutaneous nephrolithotomy. Leye Ajayi, M. Hussain, Dominic Yu, Nick Woodward, Neil Davis, Antony Goode. European Urology Association Annual Meeting. Stockholm. March 2009
Our initial experience with extended lithotomy position for percutaneous nephrolithotomy. Leye Ajayi, M. Hussain, Dominic Yu, Nick Woodward, Neil Davis, Anthony Goode. Urolithiasis Research meeting. Nice. September 2008
The true value of Hexvix® photodynamic diagnosis following intravesical Bacilli Calmette Guerin treatment for superficial bladder cancer. Eleanor Ray, Kay Thomas, Leye Ajayi, Kathryn Chatterton, M S Khan, Tim O’Brien. American Urologic Association Annual Meeting. California May 2007.
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. British association of Urological Surgeons-Glasgow 2006
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. 24th World Congress of Endourology. August 2006
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. Accepted for paper (PODIUM) presentation BAUS 2006.
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer.E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. Royal Society of Medicine Short papers meeting, December 2005.
Initial experience using the photosensitizer Hexvix® in photodynamic assisted resection of superficial bladder cancer. E Ray, L Ajayi, K Thomas, K Chatterton, S Khan, TS O’Brien. SE Thames Regional Meeting, October 2005. Runner up Packham prize awarded.
A prospective audit of flexible ureterenoscopy and holmium laser lithotripsy for the treatment of intra renal calculi.Henderson JR, Ajayi LA, Thomas K, Dasgupta P, Glass JMG, Tiptaft RC. Southeast Thames Regional audit meeting- Guilford 2005
A prospective comparison of flexible ureterenoscopy and holmium laser versus electrohydrolic lithotripsy for ESWL resistant upper tract calculi. Ajayi LA, Henderson JR, Thomas K, Dasgupta P, Glass JMG, Tiptaft RC. BAUS Glasgow 2005
The significance of the pten gene in prostate cancer. Ajayi LA, Stewart LMD, Roberts KG, Snary D, KaisaryAV. SIU section of oncology. Sharm-el-sheik, Eygpt. Oct 2003
The use of Ureteral access sheaths and flexible ureteroscopy; A marriage made in Heaven? L.Ajayi, J.Allan, B.Montgomery, H.Naerger, E.Palfrey. BAUS Glasgow 2002.
Are the clinical implications of the association between Ballanitis Xerotica Obliterans and penile cancer underestimated? Leye Ajayi, Peter Pietrzak Chryssanthos Kouriefs, Carl Rowbotham, Nicholas A Watkin. The Urological Association of South Africa Congress 21-24^th March 2002.
Regular placement of nephrostomy tube following percutaneous nephrolithotomy is unnecessary unless a specific indication exists. Leye Ajayi, Zaf Mann, Nicholas Watkin, Chris Jones, John Boyd. The Urological Association of South Africa Congress 21-24^th March 2002.
The use of Ureteral access sheaths and flexible ureteroscopy; A marriage made in Heaven? L.Ajayi, L.Lilas, J.Allan, B.Montgomery, H.Naerger, E.Palfrey. 19^th World Congress of Endourology, Bangkok, Nov 14^th-17^th 2001.
100-consective uses of sensor guide wires. M.Williams, L.Ajayi, J.Allan, B.Montgomery, H.Naerger, E.Palfrey. 19^th World Congress of Endourology, Bangkok, Nov 14^th-17^th 2001.
LOH studies on PTEN gene in prostate cancer. Ajayi LA, Stewart LMD, Roberts KG, Snary D, KaisaryAV. BAUS section of Oncology & British Prostate Group meeting, Newport. Nov 2000
Role of Atrial Natriuretic Peptide in Nocturnal Polyuria in elderly males. L.A. Ajayi, A.A. McConnell, P. Abrams, P.G. Carter. ANP conference Ottawa, Canada. Aug 2000.
Use of Microsatellite markers as Genetic markers to identify risks of tumour progression. Ajayi LA, Stewart LMD, Roberts KG, Snary D, KaisaryAV. BAUS Birmingham 2000.
DNA extraction technique using Microsatellite markers in paraffin embedded radical prostatectomy specimens. Ajayi LA, Stewart LMD, Roberts KG, Snary D, KaisaryAV. Urology research society. Royal college of Surgeons, Jan 2000
The value of DRE, PSA or both in outcome of prostate biopsy. Ajayi LA, Green JSA, Simmonds N,Wilson C, KaisaryAV. The 6th Mediterranean Congress of Urology, Cairo, Egypt, Sept 1999
Single NucleotidePolymorphism (SNP) analysis on PTEN Gene in patients with Prostate Cancer. Ajayi LA, Stewart LMD,Simmonds N, Snary D, KaisaryAV. The 6th Mediterranean Congress of Urology, Cairo, Egypt, Sept 1999

Mr Leye Ajayi, Consultant Urological Surgeon is available to be seen for consultations at Royal Free Hospital

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