Mr Reza Mirnezami
MBBS, BSC, FRCS, PHD
Consultant Colorectal and General Surgeon
Mr Reza Mirnezami is a Consultant Colorectal and Neuroendocrine Tumour Surgeon at the Royal Free Hospital and a core member of the neuroendocrine tumour multidisciplinary team at its ENETS Centre of Excellence. He receives tertiary referrals from across the UK and performs approximately 40–50 neuroendocrine tumour (NET) resections annually. His practice focuses on locally advanced and recurrent small intestinal NETs, including complex mesenteric disease involving the superior mesenteric vessels.
He is developing the Royal Free’s clinical pathway for robotic resection of small intestinal NETs and mesenteric masses. His high-volume robotic practice includes the first UK case series dedicated to robotic resection of midgut NETs. The pathway integrates specialist imaging and multidisciplinary review with selective double-balloon enteroscopy for preoperative tumour mapping. These findings inform patient selection and the extent of resection, with particular emphasis on preserving mesenteric perfusion and viable bowel.
His practice also encompasses complex open resections and a substantial volume of synchronous resections. He works closely with hepatobiliary colleagues to undertake combined bowel and liver resections in selected patients with metastatic NETs. The choice of operative approach is guided by disease distribution, vascular involvement and the objectives of surgery.
Mr Mirnezami’s research addresses operative strategy for small intestinal NETs with major mesenteric vascular involvement, the management of peritoneal metastases and the role of preoperative tumour mapping in robotic surgery. He contributes to international research through the CUT-NETS collaborative and serves as Education and Training Lead for the UK and Ireland Neuroendocrine Tumour Society. He holds a PhD from Imperial College London.
At Royal Free London, Mr Mirnezami is Head of Department for Colorectal Surgery and Chair of the Colorectal Cancer Tumour Board. He also serves as North Central London Network Director for Colorectal Cancer with the London Cancer Alliance.
Hospital Locations
Royal Free Hospital
Year qualified
2004
Country of qualification
UK
Languages spoken
English and Farsi
Specialities
- Colorectal Surgery
- General Surgery
- Neuroendocrine Tumours (NETs)
Memberships
- Royal College of Surgeons of England (RCSEng)
- Association of Coloproctology of Great Britain & Ireland (ACPGBI)
- PHIN (Private Healthcare Information Network) Access PHIN profile
Registration and licensing
GMC:6104730
Procedures offered
- Laparoscopic and open surgery for colon cancer and rectal cancer
- Laparoscopic and open surgery for inflammatory bowel disease (including but not limited to Crohn’s disease and ulcerative colitis)
- Open abdominal wall hernia surgery (including but not limited to inguinal, femoral, umbilical, epigastric and incisional hernia)
- Surgery for haemorrhoids (including Milligan-Morgan haemorrhoidectomy, Ligasure haemorrhoidectomy, THD and rubber band ligation)
- Surgery for anal fissure
- Stoma reversal
Clinical interests
- Chron's disease
- Colorectal cancer
- Inflammatory bowel disease
- Neuroendocrine Tumours (NETs)
- Ulcerative colitis
Research interests
I am passionate about clinical and translational research and I currently have an active research portfolio focused on colorectal cancer metabolism. I was awarded a PhD in 2013 for a project evaluating the role of metabolic phenotyping approaches (NMR spectroscopy and mass spectrometry) in colorectal cancer.


